Colistin-Induced Neurotoxicity in a Multidrug-Resistant UTI Patient with Cervical Cancer: A Case Report

Introduction: There has been a rise in the reappearance of multidrug-resistant Gram-negative bacteria recent years. Using polymyxins, such as colistin, last-line treatment for these infections led to renewed interest toxic effects this drug. Case Presentation: In case report, we present neurological signs and symptoms developed patient with history cervical cancer four five hours after receiving colistin treating urinary tract infection caused by MDR Pseudomonas aeruginosa colony count > 100,000/L. These included lower limb hemiparesis, facial paresthesia, decreased deep tendon reflexes, tinnitus, which were resolved on their own 24 discontinuation Antibiotic therapy was continued pipractate ciprofloxacin instead. The got discharged stable condition negative urine culture results.